In a world ravaged by a viral infection, turning its victims into undead, Alice (Jovovich), continues his journey to find survivors and lead them to safety. His mortal combat with the Umbrella Corporation to new heights, but Alice gets some unexpected help from an old friend. A new track, which promises a safe haven for the undead and takes them to Los Angeles, but when they arrive in the city is invaded by thousands of undead – and Alice and her friends are about to enter into a death trap.